Do you get less than 6 hours of sleep per night? New study says it could increase your risk of dementia

Video above: keep waking up at night? You can suffer from fragmented sleep Calling anyone who is sleep deprived: We interrupt your yawns with an important announcement.If you’re trying to get by on about six hours or less of sleep per night during the work week, you you’re preparing your brain for future failure, according to a new study published Tuesday in the journal Nature Communications. After following nearly 8,000 people for 25 years, the study found a higher risk of dementia with a “sleep duration of six hours or less at 50 and 60 years old. Compared to those who slept seven hours a night. Additionally, a short, persistent sleep duration between 50, 60, and 70 years was also associated with “a 30% increased risk of dementia,” regardless of “socio-demographic, behavioral, cardiometabolic, and mental health factors,” y including depression, according to the study. ” Sleep is important for normal brain function and is also considered important for removing toxic proteins that build up in dementias from the brain, ”said Tara Spiers-Jones, who is deputy director of the Center for Discovery Brain Sciences. the University of Edinburgh in Scotland, in a statement. Spiers-Jones was not involved in the study. “What’s the message for all of us? Signs of sleep disturbances can appear long before other clinical evidence of dementia appears, “said Tom Dening, who heads the Center for Dementia at” However, this study cannot establish a cause and effect, “said Tom Dening, who heads the Center for Dementia. said Denning, who was not involved in the study. “This may just be a very early sign of coming dementia, but it is also highly likely that poor sleep is not good for the patient. brain and makes it vulnerable to neurodegenerative diseases such as Alzheimer’s disease. ” Chicken or Egg? It is well known that people with Alzheimer’s disease suffer from sleep problems. In fact, insomnia, night wandering and daytime sleepiness are common in people with Alzheimer’s disease. ‘Alzheimer’s, as well as other cognitive disorders such as Lewy body dementia and frontal lobe dementia. According to neuroscientist Jeffrey Iliff, professor of psychiatry and behavioral sciences at the University of Washington School of Medicine. , this ‘chicken and egg’ question has been explored in previous studies, with research going both ways to be both chicken and egg proof, ”Iliff told CNN in a previous interview. “You can drive either way.” Some recent studies, however, have explored the damage that sleep deprivation can cause. People who get less REM sleep, or dream stage sleep , can be more at risk of developing dementia, according to a 2017 study. REM is the fifth stage of sleep, when the eyes move, the body warms up, breathing and pulse quicken, and the mind dreams. Healthy middle-aged adults who slept poorly for a single night produced an abundance of beta-amyloid plaques – one of the hallmarks of Alzheimer’s disease, another study published in 2017 found. -amyloid is a sticky protein compound that disrupts communication between brain cells, eventually killing cells by building up in the brain A week of disrupted sleep increased the amount of tau, another protein responsible for the tangles associated with dementia ‘Alzheimer’s, frontal lobe dementia, and Lewy body Yet another 2017 study compared markers of dementia in cerebrospinal fluid to self-reported sleep problems, and found that subjects who had problems of sleep were more likely to show signs of tau pathology, brain cell damage, and inflammation, even when other factors such as depression, co-mass. sporelle, cardiovascular disease and sleeping pills were taken into account. “Our results are consistent with the idea that poor sleep may contribute to the buildup of Alzheimer’s disease-related proteins in the brain,” Barbara Bendlin of Wisconsin Alzheimer’s Disease Research Center told CNN in a previous interview on the 2017 study. “The fact that we can find these effects in people Healthy, near-middle-age cognitive relationships suggests that these relationships appear early, possibly providing an opportunity for intervention,” Bendlin said . it adds “new information to the emerging picture” on the link between sleep deprivation and dementia, said Elizabeth Coulthard, associate professor of dementia neurology at the University of Bristol in the UK, in a communicated. “This means that at least some of the people who developed dementia probably didn’t already have it at the start of the study when their sleep was first assessed,” said Coulthard, who was not involved. in the study. “This strengthens the evidence that poor sleep in mid-age could cause or worsen dementia later in life,” she said. At present, science doesn’t There is no “sure-fire way to prevent dementia,” but people can change certain behaviors to reduce their risk, Sa ra Imarisio, who heads strategic initiatives at Alzheimer’s Research UK, said in a statement. Imarisio was not involved. under study. “The best evidence suggests that not smoking, drinking in moderation, staying mentally and physically active, eating a balanced diet, and controlling cholesterol and blood pressure levels can all help keep our brains healthy. as we get older. ”

Video above: keep waking up at night? You may suffer from fragmented sleep

Calling all those who are sleep deprived: we are interrupting your yawns with an important announcement.

If you’re trying to get by on about six hours or less of sleep per night during the work week, you’re preparing your brain for future failure, according to a new study published Tuesday in the journal Nature Communications.

After following nearly 8,000 people for 25 years, the study found a higher risk of dementia with “six hours of sleep or less at ages 50 and 60” compared to those who slept seven hours a night. .

In addition, a short, persistent sleep duration between 50, 60 and 70 years was also associated with a “30% increased risk of dementia”, independent of “socio-demographic, behavioral, cardiometabolic and mental health factors”, including depression. , according to the study. .

“Sleep is important for normal brain function and is also considered important for removing toxic proteins that build up in dementias from the brain,” said Tara Spiers-Jones, deputy director of the Center for Discovery Brain Sciences at the ‘University of Edinburgh in Scotland, in a statement. Spiers-Jones was not involved in the study.

“What’s the message for all of us? Signs of disturbed sleep can occur long before other clinical evidence of dementia appears,” said Tom Dening, who heads the Center for Dementia at the Institute of Mental Health of the University of Nottingham in the United Kingdom, in a statement.

“However, this study cannot establish a cause and effect,” said Denning, who was not involved in the study. “This may just be a very early sign of coming dementia, but it’s also very likely that poor sleep is not good for the brain and leaves it vulnerable to neurodegenerative conditions like Alzheimer’s disease. . “

Chicken or egg?

It is well known that people with Alzheimer’s disease suffer from sleep problems. In fact, insomnia, nocturnal wandering, and daytime sleepiness are common in people with Alzheimer’s disease, along with other cognitive impairments such as Lewy body dementia and frontal lobe dementia.

But does poor sleep lead to dementia – and what comes first? This “chicken and egg” question has been explored in previous studies, with research working both ways, according to neuroscientist Jeffrey Iliff, professor of psychiatry and behavioral sciences at the School of Medicine. University of Washington.

“In experimental studies, there appears to be both chicken and egg evidence,” Iliff told CNN in a previous interview. “You can drive it either way.”

Some recent studies, however, have explored the damage sleep deprivation can cause.

People who get less REM or dream-stage sleep may be at higher risk of developing dementia, according to a 2017 study. REM is the fifth stage of sleep, when the eyes move, the body warms up, breathing and pulse quicken and the mind dreams.

Healthy middle-aged adults who slept poorly for a single night produced an abundance of beta-amyloid plaques – one of the hallmarks of Alzheimer’s disease, another study published in 2017 found. -amyloid is a sticky protein compound that disrupts communication between brain cells, eventually killing cells as it builds up in the brain

A week of disturbed sleep increased the amount of tau, another protein responsible for tangles associated with Alzheimer’s disease, frontal lobe dementia and Lewy body disease, according to the study.

Another 2017 study compared markers of dementia in cerebrospinal fluid to self-reported sleep problems, and found that subjects who had sleep problems were more likely to have signs of tau pathology, brain damage. brain cells and inflammation, even when other factors such as depression, body mass, cardiovascular disease, and sleeping pills were taken into account.

“Our results are consistent with the idea that poor sleep may contribute to the buildup of Alzheimer’s disease-related proteins in the brain,” Barbara Bendlin of Wisconsin Alzheimer’s Disease Research Center told CNN in a previous interview on the 2017 study.

“The fact that we can find these effects in cognitively healthy and near middle-aged people suggests that these relationships are appearing early, possibly providing an opportunity for intervention,” said Bendlin.

‘New information’ on link to sleep deprivation

Because the new study has followed a large population over a long period of time, it adds “new information to the emerging picture” about the link between sleep deprivation and dementia, said Elizabeth Coulthard, associate professor of neurology. of dementia at the University of Bristol in the UK, in a statement.

“This means that at least some of the people who developed dementia probably didn’t already have it at the start of the study when their sleep was first assessed,” said Coulthard, who was not involved. in the study.

“It strengthens the evidence that poor sleep in middle age could cause or worsen dementia later in life,” she said.

Right now, science doesn’t have a “sure-fire way to prevent dementia,” but people can change certain behaviors to lower their risk, said Sara Imarisio, who leads strategic initiatives at Alzheimer’s Research UK, in a statement. Imarisio was not involved in the study.

“The best evidence suggests that not smoking, drinking in moderation, staying active mentally and physically, eating a balanced diet, and controlling cholesterol and blood pressure levels can all help keep our brains healthy as we age. “



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